Multiwell-MEAs with plain gold electrodes on PCB substrate are also available in 24- and 96-well format. Electrodes of 100 µm diameter with 700 µm spacing can be achieved using standard PCB circuit board production processes, which facilitates lower pricing. Originally designed mostly for cardiac myocytes, PCB arrays turned out to be suitable for neurons as well. After establishing an assay under optical control on glass bottom arrays, users can turn to the PCB arrays to run experiments at high throughput with a reasonable consumables budget.